Cystic Fibrosis and the Digestive System How does cystic fibrosis affect the digestive system?
This causes thick, sticky mucus and very salty sweat. Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.
More than a thousand known defects can affect the CFTR gene. The type of defect you or your child has may affect the severity of CF. Other genes also may play a role in the severity of the disease.
How Is Cystic Fibrosis Inherited? Every person inherits two CFTR genes—one from each parent. However, they can pass the faulty CFTR gene to their children.
A person inherits two copies of the CFTR gene—one from each parent. If each parent has a normal CFTR gene and a faulty CFTR gene, each child has a 25 percent chance of inheriting two normal genes; a 50 percent chance of inheriting one normal gene and one faulty gene; and a 25 percent chance of inheriting two faulty genes.
Risk Factors Cystic fibrosis CF affects both males and females and people from all racial and ethnic groups. However, the disease is most common among Caucasians of Northern European descent. The disease is less common among African Americans and Asian Americans.
More than 10 million Americans are carriers of a faulty CF gene. Signs, Symptoms, and Complications The signs and symptoms of cystic fibrosis CF vary from person to person and over time.
Other times, your symptoms may become more severe.
Most of the other signs and symptoms of CF happen later. Cystic Fibrosis Figure A shows the organs that cystic fibrosis can affect. Figure B shows a cross-section of a normal airway. Figure C shows an airway with cystic fibrosis. The widened airway is blocked by thick, sticky mucus that contains blood and bacteria.
This buildup of mucus makes it easier for bacteria to grow and cause infections. An infection caused by these bacteria may be a sign of CF. People who have CF have frequent bouts of sinusitis si-nu-SI-tisan infection of the sinuses.
The sinuses are hollow air spaces around the eyes, nose, and forehead. Frequent bouts of bronchitis bron-KI-tis and pneumonia nu-MO-ne-ah also can occur.
These infections can cause long-term lung damage. Some people who have CF also develop nasal polyps growths in the nose that may require surgery. Digestive System Signs and Symptoms In CF, mucus can block tubes, or ducts, in your pancreas an organ in your abdomen.
These blockages prevent enzymes from reaching your intestines. This can cause ongoing diarrhea or bulky, foul-smelling, greasy stools. Intestinal blockages also may occur, especially in newborns. Too much gas or severe constipation in the intestines may cause stomach pain and discomfort.
A hallmark of CF in children is poor weight gain and growth. These children are unable to get enough nutrients from their food because of the lack of enzymes to help absorb fats and proteins.
As CF gets worse, other problems may occur, such as: This is a condition in which the pancreas become inflamed, which causes pain. Frequent coughing or problems passing stools may cause rectal tissue from inside you to move out of your rectum.
Liver disease due to inflamed or blocked bile ducts.Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease.
respiratory failure. In the pancreas, the mucus prevents the release of digestive enzymes that allow the body to break down food and absorb vital nutrients. Symptoms of CF.
People with CF. Cystic fibrosis is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. Cystic fibrosis affects the cells that produce mucus, sweat and digestive juices. Cystic fibrosis is an inherited disease characterized by the buildup of thick, sticky mucus that can damage many of the body's organs.
The disorder's most common signs and symptoms include progressive damage to the respiratory system and chronic digestive system problems.
As part of the Cystic Fibrosis Foundation's mission to help improve the lives of people living with cystic fibrosis, the PSDC initiative taps the CF community to inform . More than 30, people in the U.S. live with cystic fibrosis (CF.) Doctors diagnose about 1, new cases each year.
CF affects the cells in your body that make mucus, sweat, and digestive fluids. Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands.
It affects mostly your lungs, pancreas, liver, intestines, sinuses, and sex organs.